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Are cells guaranteed to get at least one mitochondrion when they divide?


Does every mitochondrion in a cell contain the same DNA?How are different types of cells created from zygote?Mitochondria - are they really separate organisms that once merged into eukaryotic cells?Are mitochondria transferable between cell types, individuals and species?In cell division, are daughter cells identical?Can mitochondria be regenerated by the cell?Why isn't meiosis II called mitosis (as the chromosome number doesn't half)?Why do cells divide (or copy themselves)?Cell organels during cell reproductionHow does the zygote divide much faster than other cells?













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$begingroup$


If mitochondria exist at random within a cell, isn't there a possibility that cell division will result in a daughter cell with no mitochondria? If not, what is the process for guaranteeing at least one is present in each daughter cell? If so, what happens to that cell?










share|improve this question









$endgroup$
















    4












    $begingroup$


    If mitochondria exist at random within a cell, isn't there a possibility that cell division will result in a daughter cell with no mitochondria? If not, what is the process for guaranteeing at least one is present in each daughter cell? If so, what happens to that cell?










    share|improve this question









    $endgroup$














      4












      4








      4


      1



      $begingroup$


      If mitochondria exist at random within a cell, isn't there a possibility that cell division will result in a daughter cell with no mitochondria? If not, what is the process for guaranteeing at least one is present in each daughter cell? If so, what happens to that cell?










      share|improve this question









      $endgroup$




      If mitochondria exist at random within a cell, isn't there a possibility that cell division will result in a daughter cell with no mitochondria? If not, what is the process for guaranteeing at least one is present in each daughter cell? If so, what happens to that cell?







      cell-biology mitochondria mitosis






      share|improve this question













      share|improve this question











      share|improve this question




      share|improve this question










      asked 9 hours ago









      sourcebugsourcebug

      412




      412




















          3 Answers
          3






          active

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          6












          $begingroup$


          Isn't there a possibility that cell division will result in a daughter
          cell with no mitochondria?




          Yes, there is always the possibility. However, there must be a strong negative selection pressure against eukaryotic life that cannot achieve the proper partitioning of mitochondria, so you can imagine that there are mechanisms in place to prevent this case.



          Mitochondria are both passively and actively partitioned to daughter cells. This is understood to occur through the cytoskeleton and with the control of mitochondrial fusion and fission at key stages of the cell cycle, prior to mitosis and cytokinesis!



          Here is a great review from several years ago that addresses your question well.






          share|improve this answer











          $endgroup$












          • $begingroup$
            The review is just 5 years old. If it's "several years old" then what would you say about the waiting time to be eligible for an academic job? 😁
            $endgroup$
            – WYSIWYG
            14 mins ago



















          2












          $begingroup$

          In addition to S Pr's excellent example, I wanted to point out that some very recent research describes some special behavior in oocyte development specifically related to mitochondria selection.



          Here's a easy-to-read version:
          https://www.sciencedaily.com/releases/2019/05/190515131741.htm



          Specifically, during meiosis, the oocyte specifically "puts the mitochondria to the test" by separating all of them (fragmentation) and having each of them operate independently. (Typically mitochondria act in concert, each one potentially making up for deficiencies in their peers). Any that do not "make the cut" are eliminated, and the result is an egg cell that has the best mitochondria to pass along to the next generation.






          share|improve this answer









          $endgroup$




















            1












            $begingroup$

            A typical animal cell has 1000-2000 mitochondria. From a statistical point of view, assuming a random distribution of the mitochondria and that the cell splits in half, the probability of having 0 mitochondria is (1/2)^1000 or 9e-302. This makes it an impossibility for all practical purposes.



            With enough mitochondria, a process to ensure the cell splits roughly in half and a somewhat random distribution of mitochondria would be sufficient to get at least one mitochondria in each daughter cell.






            share|improve this answer









            $endgroup$













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              6












              $begingroup$


              Isn't there a possibility that cell division will result in a daughter
              cell with no mitochondria?




              Yes, there is always the possibility. However, there must be a strong negative selection pressure against eukaryotic life that cannot achieve the proper partitioning of mitochondria, so you can imagine that there are mechanisms in place to prevent this case.



              Mitochondria are both passively and actively partitioned to daughter cells. This is understood to occur through the cytoskeleton and with the control of mitochondrial fusion and fission at key stages of the cell cycle, prior to mitosis and cytokinesis!



              Here is a great review from several years ago that addresses your question well.






              share|improve this answer











              $endgroup$












              • $begingroup$
                The review is just 5 years old. If it's "several years old" then what would you say about the waiting time to be eligible for an academic job? 😁
                $endgroup$
                – WYSIWYG
                14 mins ago
















              6












              $begingroup$


              Isn't there a possibility that cell division will result in a daughter
              cell with no mitochondria?




              Yes, there is always the possibility. However, there must be a strong negative selection pressure against eukaryotic life that cannot achieve the proper partitioning of mitochondria, so you can imagine that there are mechanisms in place to prevent this case.



              Mitochondria are both passively and actively partitioned to daughter cells. This is understood to occur through the cytoskeleton and with the control of mitochondrial fusion and fission at key stages of the cell cycle, prior to mitosis and cytokinesis!



              Here is a great review from several years ago that addresses your question well.






              share|improve this answer











              $endgroup$












              • $begingroup$
                The review is just 5 years old. If it's "several years old" then what would you say about the waiting time to be eligible for an academic job? 😁
                $endgroup$
                – WYSIWYG
                14 mins ago














              6












              6








              6





              $begingroup$


              Isn't there a possibility that cell division will result in a daughter
              cell with no mitochondria?




              Yes, there is always the possibility. However, there must be a strong negative selection pressure against eukaryotic life that cannot achieve the proper partitioning of mitochondria, so you can imagine that there are mechanisms in place to prevent this case.



              Mitochondria are both passively and actively partitioned to daughter cells. This is understood to occur through the cytoskeleton and with the control of mitochondrial fusion and fission at key stages of the cell cycle, prior to mitosis and cytokinesis!



              Here is a great review from several years ago that addresses your question well.






              share|improve this answer











              $endgroup$




              Isn't there a possibility that cell division will result in a daughter
              cell with no mitochondria?




              Yes, there is always the possibility. However, there must be a strong negative selection pressure against eukaryotic life that cannot achieve the proper partitioning of mitochondria, so you can imagine that there are mechanisms in place to prevent this case.



              Mitochondria are both passively and actively partitioned to daughter cells. This is understood to occur through the cytoskeleton and with the control of mitochondrial fusion and fission at key stages of the cell cycle, prior to mitosis and cytokinesis!



              Here is a great review from several years ago that addresses your question well.







              share|improve this answer














              share|improve this answer



              share|improve this answer








              edited 7 hours ago

























              answered 8 hours ago









              S PrS Pr

              1,925112




              1,925112











              • $begingroup$
                The review is just 5 years old. If it's "several years old" then what would you say about the waiting time to be eligible for an academic job? 😁
                $endgroup$
                – WYSIWYG
                14 mins ago

















              • $begingroup$
                The review is just 5 years old. If it's "several years old" then what would you say about the waiting time to be eligible for an academic job? 😁
                $endgroup$
                – WYSIWYG
                14 mins ago
















              $begingroup$
              The review is just 5 years old. If it's "several years old" then what would you say about the waiting time to be eligible for an academic job? 😁
              $endgroup$
              – WYSIWYG
              14 mins ago





              $begingroup$
              The review is just 5 years old. If it's "several years old" then what would you say about the waiting time to be eligible for an academic job? 😁
              $endgroup$
              – WYSIWYG
              14 mins ago












              2












              $begingroup$

              In addition to S Pr's excellent example, I wanted to point out that some very recent research describes some special behavior in oocyte development specifically related to mitochondria selection.



              Here's a easy-to-read version:
              https://www.sciencedaily.com/releases/2019/05/190515131741.htm



              Specifically, during meiosis, the oocyte specifically "puts the mitochondria to the test" by separating all of them (fragmentation) and having each of them operate independently. (Typically mitochondria act in concert, each one potentially making up for deficiencies in their peers). Any that do not "make the cut" are eliminated, and the result is an egg cell that has the best mitochondria to pass along to the next generation.






              share|improve this answer









              $endgroup$

















                2












                $begingroup$

                In addition to S Pr's excellent example, I wanted to point out that some very recent research describes some special behavior in oocyte development specifically related to mitochondria selection.



                Here's a easy-to-read version:
                https://www.sciencedaily.com/releases/2019/05/190515131741.htm



                Specifically, during meiosis, the oocyte specifically "puts the mitochondria to the test" by separating all of them (fragmentation) and having each of them operate independently. (Typically mitochondria act in concert, each one potentially making up for deficiencies in their peers). Any that do not "make the cut" are eliminated, and the result is an egg cell that has the best mitochondria to pass along to the next generation.






                share|improve this answer









                $endgroup$















                  2












                  2








                  2





                  $begingroup$

                  In addition to S Pr's excellent example, I wanted to point out that some very recent research describes some special behavior in oocyte development specifically related to mitochondria selection.



                  Here's a easy-to-read version:
                  https://www.sciencedaily.com/releases/2019/05/190515131741.htm



                  Specifically, during meiosis, the oocyte specifically "puts the mitochondria to the test" by separating all of them (fragmentation) and having each of them operate independently. (Typically mitochondria act in concert, each one potentially making up for deficiencies in their peers). Any that do not "make the cut" are eliminated, and the result is an egg cell that has the best mitochondria to pass along to the next generation.






                  share|improve this answer









                  $endgroup$



                  In addition to S Pr's excellent example, I wanted to point out that some very recent research describes some special behavior in oocyte development specifically related to mitochondria selection.



                  Here's a easy-to-read version:
                  https://www.sciencedaily.com/releases/2019/05/190515131741.htm



                  Specifically, during meiosis, the oocyte specifically "puts the mitochondria to the test" by separating all of them (fragmentation) and having each of them operate independently. (Typically mitochondria act in concert, each one potentially making up for deficiencies in their peers). Any that do not "make the cut" are eliminated, and the result is an egg cell that has the best mitochondria to pass along to the next generation.







                  share|improve this answer












                  share|improve this answer



                  share|improve this answer










                  answered 3 hours ago









                  Reginald BlueReginald Blue

                  28127




                  28127





















                      1












                      $begingroup$

                      A typical animal cell has 1000-2000 mitochondria. From a statistical point of view, assuming a random distribution of the mitochondria and that the cell splits in half, the probability of having 0 mitochondria is (1/2)^1000 or 9e-302. This makes it an impossibility for all practical purposes.



                      With enough mitochondria, a process to ensure the cell splits roughly in half and a somewhat random distribution of mitochondria would be sufficient to get at least one mitochondria in each daughter cell.






                      share|improve this answer









                      $endgroup$

















                        1












                        $begingroup$

                        A typical animal cell has 1000-2000 mitochondria. From a statistical point of view, assuming a random distribution of the mitochondria and that the cell splits in half, the probability of having 0 mitochondria is (1/2)^1000 or 9e-302. This makes it an impossibility for all practical purposes.



                        With enough mitochondria, a process to ensure the cell splits roughly in half and a somewhat random distribution of mitochondria would be sufficient to get at least one mitochondria in each daughter cell.






                        share|improve this answer









                        $endgroup$















                          1












                          1








                          1





                          $begingroup$

                          A typical animal cell has 1000-2000 mitochondria. From a statistical point of view, assuming a random distribution of the mitochondria and that the cell splits in half, the probability of having 0 mitochondria is (1/2)^1000 or 9e-302. This makes it an impossibility for all practical purposes.



                          With enough mitochondria, a process to ensure the cell splits roughly in half and a somewhat random distribution of mitochondria would be sufficient to get at least one mitochondria in each daughter cell.






                          share|improve this answer









                          $endgroup$



                          A typical animal cell has 1000-2000 mitochondria. From a statistical point of view, assuming a random distribution of the mitochondria and that the cell splits in half, the probability of having 0 mitochondria is (1/2)^1000 or 9e-302. This makes it an impossibility for all practical purposes.



                          With enough mitochondria, a process to ensure the cell splits roughly in half and a somewhat random distribution of mitochondria would be sufficient to get at least one mitochondria in each daughter cell.







                          share|improve this answer












                          share|improve this answer



                          share|improve this answer










                          answered 1 hour ago









                          UnderminerUnderminer

                          1066




                          1066



























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